by Darren ng | Aug 12, 2026 | Supplements
Short answer: Milk thistle’s active, silybin, has a genuine evidence signal in fatty liver — but plain extract is poorly absorbed, so the delivery form largely decides whether a meaningful dose ever reaches the patient. Complexing silybin with phospholipid (a...
by Darren ng | Aug 9, 2026 | Supplements
Short answer: Alpha-lipoic acid is one of the very few nutritional actives that Malaysia’s own regulator has singled out for a mandatory warning statement. In April 2022 the Drug Control Authority directed that health-supplement products containing alpha-lipoic...
by Darren ng | Aug 4, 2026 | Supplements
Short answer: Patients on GLP-1 receptor agonist therapy eat considerably less, often eat a narrower range of foods, and digest more slowly — and the published literature suggests that combination can leave measurable gaps in vitamin D, vitamin B12, iron,...
by Darren ng | Aug 3, 2026 | Supplements
Short answer: A shelf supplement is a fixed dose in a fixed combination, formulated for a population average before anyone knew a single one of your patient’s numbers. It cannot be titrated to a ferritin result, cannot be adjusted when you retest, and cannot...
by Darren ng | Aug 3, 2026 | Supplements
Short answer: Resveratrol is a plant polyphenol — a stilbene concentrated in grape skins and Japanese knotweed — best known in the longevity field as a sirtuin activator studied alongside the NAD+ pathway. Its practical problem is absorption: although the gut takes up...
by Darren ng | Aug 3, 2026 | Supplements
Short answer: Quercetin is one of the clearest examples in the supplement world of a promising molecule held back by poor delivery. It is a flavonoid that dissolves badly in water, is heavily metabolised in the gut wall and liver within minutes of being absorbed, and...
