by Darren ng | Aug 3, 2026 | Compounding Pharmacy
Short answer: When a patient reacts to a medicine or supplement, the active ingredient is not always the culprit. The reaction may be to an excipient — a filler, dye, preservative, binder or coating the manufacturer added for reasons that have nothing to do with the...
by Darren ng | Aug 3, 2026 | Supplements
Short answer: Resveratrol is a plant polyphenol — a stilbene concentrated in grape skins and Japanese knotweed — best known in the longevity field as a sirtuin activator studied alongside the NAD+ pathway. Its practical problem is absorption: although the gut takes up...
by Darren ng | Aug 3, 2026 | Supplements
Short answer: Quercetin is one of the clearest examples in the supplement world of a promising molecule held back by poor delivery. It is a flavonoid that dissolves badly in water, is heavily metabolised in the gut wall and liver within minutes of being absorbed, and...
by Darren ng | Aug 3, 2026 | Supplements
Short answer: Curcumin is the textbook example of a good molecule with a bad delivery profile. It is strongly fat-soluble and almost insoluble in water, it is metabolised and cleared quickly once it does get in, and the result is that most of a standard oral dose...
by Darren ng | Aug 3, 2026 | Compounding Pharmacy
Short answer: In a topical preparation, the base is not inert packaging around the active — it is the single biggest determinant of whether the active ever reaches its target. The skin is built to keep things out, and its outermost layer, the stratum corneum, is a...
